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Tag: molecular modelling

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Macinchem Blog Uncategorised

Conformational Design in Drug Discovery 2024

16 October 202316 October 2023 chris

Any interesting meeting from RSC BMCS, Conformational Design has played a key role in the medicinal chemistry of small molecule clinical candidates over the last

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Macinchem Blog Reviews Science Apps

SCM on Apple Silicon

14 October 202314 October 2023 chris

Software for Chemistry and Materials (SCM) are the developers of the Amsterdam Modeling Suite a very highly regarded computational suite used by academic and industrial

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Macinchem Blog Science Apps

BioSimSpace and Sire 2023.3.0 released

4 July 20234 July 2023 chris

New features include support for alchemical absolute binding free energies, full trajectory read, write and editing support, search by smiles and smarts, complete units grammar

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Macinchem Blog Science Apps

MolPainter and MolSolvator

22 April 202322 April 2023 chris

MolPainter is a novel GUI tool for constructing layered molecular systems represented using PDB files, it can be used to construct multilayer molecular systems. MolPainter

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Reviews Science Apps Software Reviews

Scientific Computing and Modelling Software

25 March 20231 April 2023 chris

It is sometimes difficult to keep the website up to date with some of the software that I don’t use and so I was delighted

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Macinchem Blog Reviews Science Apps Software Reviews

Review of MOE 2018.01

22 March 20231 April 2023 chris

The 2018.01 release of Chemical Computing Group’s Molecular Operating Environment (MOE) software includes a number of new features, enhancements and changes. Mac OSX 10.6 and Windows XP

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Reviews Science Apps Software Reviews

MOE 2011 Review

17 March 202311 October 2023 chris

The 2011.10 release of Chemical Computing Group’s Molecular Operating Environment (MOE) software includes a number of new features, enhancements and changes, I’ve had a quick look at

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Reviews Science Apps Software Reviews

MOE 2010.10 Release review

17 March 20238 June 2023 chris

I’ve been using the latest update to MOE from Chemical Computing Group for a while now and i thought I’d post a few impressions. The published new

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Reviews Science Apps Software Reviews

MOE Review (2009.10 release)

17 March 202315 September 2023 chris

I’ve been using the latest update to MOE from Chemical Computing Group for a while now and i thought I’d post a few impressions. Perhaps the most

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Reviews Science Apps Software Reviews

MOE 2009 update

17 March 20237 May 2023 chris

Some time ago I wrote a review of MOE the molecular modelling package from Chemical Computing Group, recently CCG announced and update and I thought it would be

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  • View post by on Bluesky

    @macinchem.bsky.social 2 days

    Avogadro 2.0.0 released

    Avogadro is a free and open source molecular editor and visualization tool. The new release of Avogadro 2, is a major update, and includes major changes, a revised interface,...
  • View post by on Bluesky

    @macinchem.bsky.social 4 days

    Looking at mlxmolkit — GPU-accelerated molecular clustering on Apple Silicon

    I've written several posts on the various options for clustering molecules...

    https://macinchem.org/2026/04/03/looking-at-mlxmolkit-gpu-accelerated-molecular-clustering-on-apple-silicon/
  • View post by on Bluesky

    @macinchem.bsky.social 6 days

    RSC CICAG Chemical Structure Representations Meeting 2026 

    I've just signed up for the meeting, hope to see you there at Burlington House, London, UK Wednesday 8th April 2026 A one-day conference...

    https://macinchem.org/2026/04/01/rsc-cicag-chemical-structure-representations-meeting-2026-2/
  • View post by on Bluesky

    @macinchem.bsky.social 7 days

    Mole2D molecule drawing package

    Mole2D is a lightweight molecule drawing package written in Python and PyQt6. All code is on GitHub https://github.com/sfmlab/mole2d and it requires RDKit and PyQt6.. PubChem lookup...

    https://macinchem.org/2026/03/31/mole2d-molecule-drawing-package/
  • View post by on Bluesky

    @macinchem.bsky.social 1 week

    RDKit Updated

    An update to RDKit has been released 2026_03_1 (Q1 2026). Highlights A significant number of known SMILES canonicalization problems were resolved. It's now possible to provide your own matching...
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Recent Posts

  • RSC CICAG Chemical Structure Representations Meeting 2026 
  • Avogadro 2.0.0 released
  • Looking at mlxmolkit — GPU-accelerated molecular clustering on Apple Silicon
  • RSC CICAG Chemical Structure Representations Meeting 2026 
  • Mole2D molecule drawing package
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  • RSC CICAG Chemical Structure Representations Meeting 2026 
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  • RSC CICAG Chemical Structure Representations Meeting 2026 
  • Mole2D molecule drawing package
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