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Hints and Tutorials Jupyter Notebook Macinchem Blog

CNotebook integrating OpenEye toolkits into Jupyter

3 February 20263 February 2026 chris

CNotebook provides chemistry visualization for Jupyter Notebooks and Marimo using the OpenEye Toolkits. Import the package and your molecular data will automatically render as chemical

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Hints and Tutorials Jupyter Notebook Macinchem Blog Science Apps

Visual Studio Code extension that renders SMILES strings

30 January 202630 January 2026 chris

MolView – SMILES Preview is a Visual Studio Code extension that renders SMILES (Simplified Molecular Input Line Entry System) strings as molecular structure diagrams on

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Data Analysis Tools Hints and Tutorials Macinchem Blog Vortex Scripts

Storing Vortex scripts outside the Vortex file system

28 January 202628 January 2026 chris

At least on a Mac the default place to store Vortex scripts is in the vortex folder ~/vortex/scripts Any folder/scripts you put in the vortex/scripts

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Hints and Tutorials Jupyter Notebook Macinchem Blog

A Jupyter Notebook to access structures and data from the Idler master worksheet

26 January 202628 January 2026 chris

There was an interesting publication from the Todd group at UCL on Chemrxiv “Idler Compounds: A Simple Protocol for Openly Sharing Fridge Contents for Cross-Screening”

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Hints and Tutorials Macinchem Blog Other Tips

Update an Expired Certificate Error on HP Printer using a Mac

5 January 202616 January 2026 chris

This morning I tried to print something to my HP LaserJet Pro printer and got an error. A quick search of the HP website suggested

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Hints and Tutorials Macinchem Blog

RDMA over Thunderbolt support is now in macOS 26.2

19 December 202519 December 2025 chris

Remote direct memory access (RDMA) is direct memory access from the memory of one computer into that of another without involving either computer’s operating system. This permits high-throughput, low-latency memory access over

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Data Analysis Tools Hints and Tutorials Macinchem Blog Vortex Scripts

Vortex script for Hit expansion

9 December 20259 December 2025 chris

One of the frequent situations after running a screen is you have a list of hits and you want to select related analogues to explore

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Hints and Tutorials Macinchem Blog

External drives for Mac

30 November 202530 November 2025 chris

I’ve updated the page describing my testing of various external hard drive options. https://macinchem.org/wp-admin/post.php?post=1899 On my Mac Studio M2 Ultra the ACASIS 80Gbps M.2 NVMe

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Hints and Tutorials Macinchem Blog

External SSD drives

21 November 202521 November 2025 chris

I’ve just purchased another external hard drive, after reviewing options I ended up buying another Acacias enclosure with the Crucial P310 4TB SSD M.2 2280

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Data Analysis Tools Hints and Tutorials Macinchem Blog Science Apps

TabPFN-2.5

10 November 202510 November 2025 chris

I’ve reviewed TabPFN in the past. https://macinchem.org/2025/02/06/looking-at-tabpfn and I noticed there was a recent update. TabPFN is a foundation model  trained on around 130,000,000 synthetically generated

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    CNotebook integrating OpenEye toolkits into Jupyter

    CNotebook provides chemistry visualization for Jupyter Notebooks and Marimo using the OpenEye Toolkits. Import the package and your molecular data will...

    CNotebook integrating OpenEye toolkits into Jupyter

    CNotebook provides chemistry visualization for Jupyter Notebooks and Marimo using the OpenEye Toolkits. Import the package and your molecular data will automatically render as chemical structures without additional configuration. Supports...

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    Cambridge Cheminformatics Meeting

    The next Cambridge Cheminformatics meeting is on 18 February 2026, 4-5.30pm UK time, Hybrid (at the CCDC on Union Road, Cambridge/via Zoom) More details of the meetings can be...

    Cambridge Cheminformatics Meeting

    The next Cambridge Cheminformatics meeting is on 18 February 2026, 4-5.30pm UK time, Hybrid (at the CCDC on Union Road, Cambridge/via Zoom) More details of the meetings can be found...

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    Visual Studio Code extension that renders SMILES strings

    MolView - SMILES Preview is a Visual Studio Code extension that renders SMILES (Simplified Molecular Input Line Entry System) strings as...

    Visual Studio Code extension that renders SMILES strings

    MolView - SMILES Preview is a Visual Studio Code extension that renders SMILES (Simplified Molecular Input Line Entry System) strings as molecular structure diagrams on hover. This means that you...

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    Storing Vortex scripts outside the Vortex file system. macinchem.org/2026/01/28/s...

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