The latest (6th) Cache challenge has been released. The target is SETDB1

Participants are asked to find molecules occupying one or multiple subcavities of the histone binding groove of the SETDB1 triple Tudor domain (TTD).

https://cache-challenge.org/challenges/finding-ligands-targeting-the-triple-tudor-domain-of-setdb1

The structure above was displayed using the brilliant 3Dmol.js (https://3dmol.csb.pitt.edu) Only a few days left Application closes 2024-06-22

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