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2023
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Installing local LLM on Apple Silicon

Data Analysis Tools Macinchem Blog

Installing local LLM on Apple Silicon

11 December 202311 December 2023 chris

Great video by Alex Ziskind on installing a local large language models on Apple Silicon.

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dock-postprocess

7 September 20267 September 2026 chris

Updated Mac mini and Mac Studio

26 August 202626 August 2026 chris

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View post by on Bluesky

@macinchem.bsky.social 2 weeks

Updated Mac mini and Mac Studio

Apple have announced new Mac mini and Mac Studio machines. Mac mini has either M5 Pro chip or M6 chip M5 Pro 15‑core CPU with 5 super cores and 10 performance...

https://macinchem.org/2026/08/26/updated-mac-mini-and-mac-studio/
View post by on Bluesky

@macinchem.bsky.social 2 weeks

Installing the OpenADMET PXR anvil prediction

I had a couple of issues installing the PXR model from OpenAMET on my Apple Silicon Mac (https://huggingface.co/openadmet/pxr-chemeleon-baseline) so I thought I'd...

https://macinchem.org/2026/08/25/installing-the-openadmet-pxr-anvil-prediction/
View post by on Bluesky

@macinchem.bsky.social 2 weeks

mlxmolkit updated

mlxmolkit is a GPU-accelerated molecular toolkit on Apple Silicon, it is a port of nvMolKit that uses Cuda. There are now three pipelines Molecular Clustering — Morgan FP → Tanimoto...

https://macinchem.org/2026/08/25/mlxmolkit-updated/
View post by on Bluesky

@macinchem.bsky.social 2 weeks

Some conferences and meetings that might be of interest.

9th Artificial Intelligence in Chemistry Symposium (https://www.rscbmcs.org/events/aichem9/) Wednesday 2nd – Friday 4th September 2026,...

https://macinchem.org/2026/08/23/some-conferences-and-meetings-that-might-be-of-interest/
View post by on Bluesky

@macinchem.bsky.social 2 weeks

Is anyone else picking blackberries, seems to be a very good year.

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dock-postprocess
Updated Mac mini and Mac Studio
Installing the OpenADMET PXR anvil prediction
mlxmolkit updated
Some conferences and meetings that might be of interest.

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dock-postprocess
Updated Mac mini and Mac Studio
Installing the OpenADMET PXR anvil prediction
mlxmolkit updated
Some conferences and meetings that might be of interest.

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