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2023
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Installing local LLM on Apple Silicon

Data Analysis Tools Macinchem Blog

Installing local LLM on Apple Silicon

11 December 202311 December 2023 chris

Great video by Alex Ziskind on installing a local large language models on Apple Silicon.

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Hints and Tutorials Macinchem Blog

A couple of interesting posts

2 November 20262 November 2026 chris

Macinchem Blog Science Apps

Burette Updated

24 October 202624 October 2026 chris

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@macinchem.bsky.social 1 week

Burette Updated

Burette is a macOS desktop app and Quick Look extension for molecular previews: Mol* 3D, xyzrender SVG, and RDKit grids. There is a review of Burette here it can...
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@macinchem.bsky.social 1 week

Avogadro Updated

Avogadro is an advanced open source molecular editor and visualization tool. Download and installation instructions are here...
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@macinchem.bsky.social 2 weeks

OpenBind Blind Challenge: Zika virus NS2B-NS3 protease

On October 14th the OpenBind Blind Challenge was launched, the target is the Zika virus NS2B-NS3 protease. This challenge focuses on predicting how...
View post by on Bluesky

@macinchem.bsky.social 3 weeks

An Updated Jupyter Notebook for docking

In 2020 as a result of lockdown I was asked to help create a course for MRes students as an introduction to computer-aided drug design [DOI] that they all...
View post by on Bluesky

@macinchem.bsky.social 3 weeks

Icms2yield AI-Predicted Full-Spectrum UV Correction Factors: An Analyte-Standard-Free Framework for Reaction Yield Quantification

https://macinchem.org/2026/10/13/icms2yield-ai-predicted-full-spectrum-uv-correction-factors-an-analyte-standard-free-framework-for-reaction-yield-quantification/

Recent Posts

A couple of interesting posts
Burette Updated
Avogadro Updated
OpenBind Blind Challenge: Zika virus NS2B-NS3 protease
An Updated Jupyter Notebook for docking

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A couple of interesting posts
Burette Updated
Avogadro Updated
OpenBind Blind Challenge: Zika virus NS2B-NS3 protease
An Updated Jupyter Notebook for docking

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