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Tag: rdkit

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Hints and Tutorials Jupyter Notebook Macinchem Blog Science Apps

Visual Studio Code extension that renders SMILES strings

30 January 202630 January 2026 chris

MolView – SMILES Preview is a Visual Studio Code extension that renders SMILES (Simplified Molecular Input Line Entry System) strings as molecular structure diagrams on

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Macinchem Blog Science Apps

Software sustainability fund

29 January 202629 January 2026 chris

A while back I wrote a post on the problems with maintaining scientific software, this seemed to strike a chord and I got a lot

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Hints and Tutorials Jupyter Notebook Macinchem Blog

A Jupyter Notebook to access structures and data from the Idler master worksheet

26 January 202628 January 2026 chris

There was an interesting publication from the Todd group at UCL on Chemrxiv “Idler Compounds: A Simple Protocol for Openly Sharing Fridge Contents for Cross-Screening”

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Macinchem Blog meetings

Joining or Renewing RSC membership

19 November 202519 November 2025 chris

It is that time of the year when Royal Society of Chemistry membership forms arrive in the letterbox. Most people don’t join any of the

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Hints and Tutorials Macinchem Blog

nvMolKit: a core set of GPU-accelerated RDKit functions

11 September 202518 September 2025 chris

An interesting post from Nvidia. nvMolKit, is a standalone, GPU-accelerated library that delivers 1-4 orders of magnitude of acceleration across five key functions: Morgan Fingerprinting,

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Hints and Tutorials Macinchem Blog

Cheminformatics tools that work natively with Google tools such as Sheets and BigQuery

31 March 202531 March 2025 chris

Whilst there are a number of chemistry aware spreadsheets Vortex, Stardrop, Datawarrior, InstantJChem, molsoft etc. many people still use Excel or Google sheets. Vexo is

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Data Analysis Tools Hints and Tutorials Jupyter Notebook Macinchem Blog Vortex Scripts

Searching a local copy of PubChem

17 February 202524 February 2025 chris

PubChem is an invaluable source of information about 99 million molecules accessible via a website or programmatically. PubChem is an open chemistry database at the National Institutes

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Data Analysis Tools Hints and Tutorials Jupyter Notebook Macinchem Blog Software Reviews

Looking at TabPFN

6 February 202517 February 2025 chris

TabPFN is a foundation model  trained on around 130,000,000 synthetically generated datasets that mimic “real world” tabular data. These datasets sampled dataset size and number

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Jupyter Notebook Macinchem Blog Science Apps

ShEPhERD: Shape, Electrostatics, and Pharmacophore Explicit Representation Diffusion

23 November 202423 November 2024 chris

A really interesting preprint caught my attention from Connor Coley’s group at MIT. ShEPhERD diffusing shape, electrostatics, and pharmacophores for bioisosteric drug design https://arxiv.org/abs/2411.04130v1 …

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Hints and Tutorials Macinchem Blog

Using lwreg with the RDKit cartridge

31 October 202431 October 2024 chris

Fabulous blog post from Greg Landrum, Includes a tutorial on installing PostgreSQL and the cartridge with conda. This post shows how to use the RDKit

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Recent Posts

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  • Visual Studio Code extension that renders SMILES strings
  • Software sustainability fund
  • Storing Vortex scripts outside the Vortex file system
  • Supporting LIGAND-AI’s search for ligands for understudied targets
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    Cambridge Cheminformatics Meeting

    The next Cambridge Cheminformatics meeting is on 18 February 2026, 4-5.30pm UK time, Hybrid (at the CCDC on Union Road, Cambridge/via Zoom) More details of the meetings can be...

    Cambridge Cheminformatics Meeting

    The next Cambridge Cheminformatics meeting is on 18 February 2026, 4-5.30pm UK time, Hybrid (at the CCDC on Union Road, Cambridge/via Zoom) More details of the meetings can be found...

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    Visual Studio Code extension that renders SMILES strings

    MolView - SMILES Preview is a Visual Studio Code extension that renders SMILES (Simplified Molecular Input Line Entry System) strings as...

    Visual Studio Code extension that renders SMILES strings

    MolView - SMILES Preview is a Visual Studio Code extension that renders SMILES (Simplified Molecular Input Line Entry System) strings as molecular structure diagrams on hover. This means that you...

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    Scientific software sustainability fund macinchem.org/2026/01/29/s...

    Software sustainability fund – Macs in Chemistry

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    Storing Vortex scripts outside the Vortex file system. macinchem.org/2026/01/28/s...

    Storing Vortex scripts outside the Vortex file system – Macs in Chemistry

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    Interesting post from the ChEMBL team. macinchem.org/2026/01/27/s...

    Supporting LIGAND-AI’s search for ligands for understudied targets – Macs in Chemistry

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