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Macinchem Blog Other Tips Science Apps

Cheminformatics Microservice V3: a web portal for chemical structure manipulation and analysis

5 February 20265 February 2026 chris

There is an interesting paper in Journal of Cheminformatics  J Cheminform 17, 142 (2025). https://doi.org/10.1186/s13321-025-01094-1 Cheminformatics Microservice V3 aims to provide easily accessible and reproducible cheminformatics tools.

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Hints and Tutorials Jupyter Notebook Macinchem Blog

CNotebook integrating OpenEye toolkits into Jupyter

3 February 20263 February 2026 chris

CNotebook provides chemistry visualization for Jupyter Notebooks and Marimo using the OpenEye Toolkits. Import the package and your molecular data will automatically render as chemical

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Hints and Tutorials Jupyter Notebook Macinchem Blog Science Apps

Visual Studio Code extension that renders SMILES strings

30 January 202630 January 2026 chris

MolView – SMILES Preview is a Visual Studio Code extension that renders SMILES (Simplified Molecular Input Line Entry System) strings as molecular structure diagrams on

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Macinchem Blog Science Apps

Software sustainability fund

29 January 202629 January 2026 chris

A while back I wrote a post on the problems with maintaining scientific software, this seemed to strike a chord and I got a lot

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Hints and Tutorials Jupyter Notebook Macinchem Blog

A Jupyter Notebook to access structures and data from the Idler master worksheet

26 January 202628 January 2026 chris

There was an interesting publication from the Todd group at UCL on Chemrxiv “Idler Compounds: A Simple Protocol for Openly Sharing Fridge Contents for Cross-Screening”

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Macinchem Blog meetings

Joining or Renewing RSC membership

19 November 202519 November 2025 chris

It is that time of the year when Royal Society of Chemistry membership forms arrive in the letterbox. Most people don’t join any of the

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Hints and Tutorials Macinchem Blog

MayaChemTools updated

2 October 20252 October 2025 chris

The excellent MayChemTools has been updated MayaChemTools is a growing collection of Perl and Python scripts, modules, and classes to support a variety of day-to-day computational discovery needs. The

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Macinchem Blog Science Apps

BindFlow

29 September 202529 September 2025 chris

Binding free energy calculations are challenging so always good to efforts in this area https://www.biorxiv.org/content/10.1101/2025.09.25.678545v1 We present BindFlow, a Python-based software for automated absolute binding

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Hints and Tutorials Macinchem Blog

nvMolKit: a core set of GPU-accelerated RDKit functions

11 September 202518 September 2025 chris

An interesting post from Nvidia. nvMolKit, is a standalone, GPU-accelerated library that delivers 1-4 orders of magnitude of acceleration across five key functions: Morgan Fingerprinting,

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Hints and Tutorials Macinchem Blog Science Apps

ORCA Python Interface

16 August 2025 chris

The ORCA Python Interface (OPI) is a Python library to create input and parse output of ORCA. It is designed as an open source community effort

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  • Cheminformatics Microservice V3: a web portal for chemical structure manipulation and analysis
  • Xcode 26.3 unlocks the power of agentic coding
  • ChemDoodle 2D v12.10 Update
  • CNotebook integrating OpenEye toolkits into Jupyter
  • Cambridge Cheminformatics Meeting
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    CNotebook integrating OpenEye toolkits into Jupyter

    CNotebook provides chemistry visualization for Jupyter Notebooks and Marimo using the OpenEye Toolkits. Import the package and your molecular data will...

    CNotebook integrating OpenEye toolkits into Jupyter

    CNotebook provides chemistry visualization for Jupyter Notebooks and Marimo using the OpenEye Toolkits. Import the package and your molecular data will automatically render as chemical structures without additional configuration. Supports...

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    Cambridge Cheminformatics Meeting

    The next Cambridge Cheminformatics meeting is on 18 February 2026, 4-5.30pm UK time, Hybrid (at the CCDC on Union Road, Cambridge/via Zoom) More details of the meetings can be...

    Cambridge Cheminformatics Meeting

    The next Cambridge Cheminformatics meeting is on 18 February 2026, 4-5.30pm UK time, Hybrid (at the CCDC on Union Road, Cambridge/via Zoom) More details of the meetings can be found...

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    Visual Studio Code extension that renders SMILES strings

    MolView - SMILES Preview is a Visual Studio Code extension that renders SMILES (Simplified Molecular Input Line Entry System) strings as...

    Visual Studio Code extension that renders SMILES strings

    MolView - SMILES Preview is a Visual Studio Code extension that renders SMILES (Simplified Molecular Input Line Entry System) strings as molecular structure diagrams on hover. This means that you...

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    Scientific software sustainability fund macinchem.org/2026/01/29/s...

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    Storing Vortex scripts outside the Vortex file system. macinchem.org/2026/01/28/s...

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