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Tag: cheminformatics

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Data Analysis Tools Macinchem Blog

Isambard-AI and Dawn AIRR supercomputers: Innovator route

6 November 20256 November 2025 chris

Isambard-AI and Dawn AIRR supercomputers: Innovator route Apply for up to 150,000 graphics processing unit hours on the Isambard-AI and Dawn supercomputers for artificial intelligence

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Data Analysis Tools Macinchem Blog Science Apps

A few updates

5 November 20255 November 2025 chris

Alvascience recently released a new major version of our tool, alvaModel, our software tool to build, compare, and deploy QSAR/QSPR Models (https://www.alvascience.com/alvamodel/).  New Modeling CapabilitiesRegression

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Macinchem Blog

OpenADMET Challenge

5 October 20255 October 2025 chris

OpenADMET have just announced the ExpansionRx-OpenADMET blind challenge in partnership with Expansion Therapeutics. Expansion Therapeutics have decided to make all the ADMET publicly available. “We

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Hints and Tutorials Macinchem Blog

MayaChemTools updated

2 October 20252 October 2025 chris

The excellent MayChemTools has been updated MayaChemTools is a growing collection of Perl and Python scripts, modules, and classes to support a variety of day-to-day computational discovery needs. The

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Macinchem Blog Science Apps

BindFlow

29 September 202529 September 2025 chris

Binding free energy calculations are challenging so always good to efforts in this area https://www.biorxiv.org/content/10.1101/2025.09.25.678545v1 We present BindFlow, a Python-based software for automated absolute binding

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Data Analysis Tools Hints and Tutorials Macinchem Blog

ChEMBL 36 is out

26 September 202526 September 2025 chris

One of the most useful databases for anyone involved in studies involved in biologically active molecules. ChEMBL is a manually curated database of bioactive molecules

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Macinchem Blog Science Apps

chemfp 5.0 released

25 September 202526 September 2025 chris

Version 5.0 has just been released, Chemfp is a fast and comprehensive Python package for cheminformatics fingerprints https://chemfp.com/docs/whats_new_in_50.html The main additions to chemfp 5.0 are:

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Hints and Tutorials Macinchem Blog

nvMolKit: a core set of GPU-accelerated RDKit functions

11 September 202518 September 2025 chris

An interesting post from Nvidia. nvMolKit, is a standalone, GPU-accelerated library that delivers 1-4 orders of magnitude of acceleration across five key functions: Morgan Fingerprinting,

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Macinchem Blog meetings

AI meetings in Cambridge

18 August 2025 chris

Two free meetings at the start of September. Full details here https://www.c-inf.net and on the 4th September The first event of Michaelmas term with two

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Data Analysis Tools Hints and Tutorials Macinchem Blog Vortex Scripts

Selecting random clusters from a large dataset in Vortex

18 July 2025 chris

When making selections from large datasets it is worth mentioning that as datasets get larger a simple random selection is often the best (and quickest)

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    Isambard-AI and Dawn AIRR supercomputers: Innovator route

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    Another update

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    The latest Nobel prizes for economics highlight how innovation and support for science drives growth. A timely reminder to invest in research. www.nature.com/articles/d41...

    Economics Nobel prize won by researchers who showed how science boosts growth

    Joel Mokyr, Philippe Aghion and Peter Howitt share economics prize for work that underlines the importance of investing in research and development.

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    Use the Foundation Models framework to access the on-device LLM that powers Apple Intelligence.

    https://macinchem.org/2025/10/08/use-the-foundation-models-framework-to-access-the-on-device-llm-that-powers-apple-intelligence/

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