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Use the Foundation Models framework to access the on-device LLM that powers Apple Intelligence.

8 October 2025 chris

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Running Qwen3.5-397B on a M3 MacBook Pro

22 March 202622 March 2026 chris

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WWDC26

Apple have announced that WWDC26 will take place on June 8-12, 2026. You can follow on the Apple Developer app, Apple website, and YouTube channel....
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Running Qwen3.5-397B on a M3 MacBook Pro

A while back Apple published a paper entitled LLM in a flash: Efficient Large Language Model Inference with Limited Memory [DOI] This paper tackles the challenge of...

https://macinchem.org/2026/03/22/running-qwen3-5-397b-on-a-m3-macbook-pro/
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RSC CICAG Chemical Structure Representations Meeting 2026

This meeting will be held at Burlington House, London, UK on Wednesday 8th April 2026. A one-day conference on Chemical Structure...
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OpenADMET Blind Challenge: Predicting PXR Induction

The next OpenADMET blind challenge focuses on predicting human Pregnane-X Receptor (hPXR) induction. The pregnane X receptor (hPXR) is the major...
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OpenFold3-preview

OpenFold3-preview is a biomolecular structure prediction model aiming to be a bitwise reproduction of DeepMind'sAlphaFold3, developed by the AlQuraishi Lab at Columbia University and the OpenFold consortium. This research...