There have been a few comments about an older blog posting concerning EBioTools so I thought I’d bump it to the top of the list.

EBioTools is a compilation of bioinformatics software that has been packaged for easy installation on Mac OS X. It covers many areas, from simple sequence analysis to RNA folding and sequence assembly.

The included software is:

• Name Version
• Boost1.3.41
• Clustal W1.83.UNIX
• PHYLIP3.6b
• EMBOSS5.0.0
• EMBOSS.kaptain0.98
• gd2.0.35
• Glimmer3.02
• HMMER2.3.2
• INFERNAL0.7
• Jmol11.2.12
• Kalign2
• Kaptain0.72
• MrBayes3.1.2
• MRSr482
• MUSCLE3.6
• NCBI Tools2.2.16
• NEdit5.5
• Primer31.1.2
• sim42003-09-21
• soap4r1.5.8
• Staden1.7.0
• T-COFFEE5.05
• ViennaRNA1.6.5

As mentioned in the comments added to the older post “EBioTools works under Snow Leopard and Lion but Staden is broken because Apple changed several Libraries to make the MacOSX core "smaller". Most issues are due to Apple changing graphic libraries.”

Users might also be interested in eBioX which brings easy-to-use sequence analysis to Mac-using biologists. It features an editor for sequences and multiple alignments, and graphical viewers for trace files and molecule structures. Many popular file formats are supported. Databases can be created locally or queried over the network, both for metadata and homology (BLAST). Analysis functions include searching for patterns, primers, restriction sites and repeats, translation and back translation, calculating DNA melting temperature, dot plots, as well as aligning sequences (multiple, local and global). Multiple alignments can be created by several of the most popular algorithms